AustralieFrV1, Main, Exploration, bibRecord, 003F87

Reduced-intensity conditioning and HLA-matched haemopoietic stem-cell transplantation in patients with chronic granulomatous disease: a prospective multicentre study

Identifieur interne : 003F87 ( Main/Exploration ); précédent : 003F86; suivant : 003F88

Reduced-intensity conditioning and HLA-matched haemopoietic stem-cell transplantation in patients with chronic granulomatous disease: a prospective multicentre study

Auteurs : Tayfun Güngör [Suisse] ; Pierre Teira [Canada] ; Mary Slatter [Royaume-Uni] ; Georg Stussi [Suisse] ; Polina Stepensky [Israël] ; Despina Moshous [France] ; Clementien Vermont [Pays-Bas] ; Imran Ahmad [Canada] ; Peter J. Shaw [Australie] ; José Marcos Telles Da Cunha [Brésil] ; Paul G. Schlegel [Allemagne] ; Rachel Hough [Royaume-Uni] ; Anders Fasth [Suède] ; Karim Kentouche [Allemagne] ; Bernd Gruhn [Allemagne] ; Juliana F. Fernandes [Brésil] ; Silvy Lachance [Canada] ; Robbert Bredius [Pays-Bas] ; Igor B. Resnick [Israël] ; Bernd H. Belohradsky [Allemagne] ; Andrew Gennery [Royaume-Uni] ; Alain Fischer [France] ; H. Bobby Gaspar [Royaume-Uni] ; Urs Schanz [Suisse] ; Reinhard Seger [Suisse] ; Katharina Rentsch [Suède] ; Paul Veys [Royaume-Uni] ; Elie Haddad [Canada] ; Michael H. Albert [Allemagne] ; Moustapha Hassan [Suède]

Source :

Lancet : (British edition) [ 0140-6736 ] ; 2014.

RBID : Pascal:14-0052843

Descripteurs français

Pascal (Inist)
- Conditionnement atténué, Système HLA, Système histocompatibilité majeur, Homogreffe, Cellule hématopoïétique, Cellule souche, Granulomatose chronique, Homme, Malade, Prospective, Etude multicentrique, Médecine, Granulomatose chronique familiale.
Wicri :
- topic : Cellule souche, Homme, Prospective, Médecine.

English descriptors

KwdEn :
- Chronic granulomatous disease, HLA-System, Hematopoietic cell, Homograft, Human, Major histocompatibility system, Medicine, Multicenter study, Non myeloablative treatment, Patient, Prospective, Stem cell.

Abstract

Background In chronic granulomatous disease allogeneic haemopoietic stem-cell transplantation (HSCT) in adolescents and young adults and patients with high-risk disease is complicated by graft-failure, graft-versus-host disease (GVHD), and transplant-related mortality. We examined the effect of a reduced-intensity conditioning regimen designed to enhance myeloid engraftment and reduce organ toxicity in these patients.

Affiliations:

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Le document en format XML

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<affiliation wicri:level="1"><inist:fA14 i1="14"><s1>Department of Paediatrics, Jena University Hospital</s1>
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<author><name sortKey="Gruhn, Bernd" sort="Gruhn, Bernd" uniqKey="Gruhn B" first="Bernd" last="Gruhn">Bernd Gruhn</name>
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<author><name sortKey="Fernandes, Juliana F" sort="Fernandes, Juliana F" uniqKey="Fernandes J" first="Juliana F." last="Fernandes">Juliana F. Fernandes</name>
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<author><name sortKey="Lachance, Silvy" sort="Lachance, Silvy" uniqKey="Lachance S" first="Silvy" last="Lachance">Silvy Lachance</name>
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<author><name sortKey="Bredius, Robbert" sort="Bredius, Robbert" uniqKey="Bredius R" first="Robbert" last="Bredius">Robbert Bredius</name>
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<author><name sortKey="Resnick, Igor B" sort="Resnick, Igor B" uniqKey="Resnick I" first="Igor B." last="Resnick">Igor B. Resnick</name>
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<author><name sortKey="Belohradsky, Bernd H" sort="Belohradsky, Bernd H" uniqKey="Belohradsky B" first="Bernd H." last="Belohradsky">Bernd H. Belohradsky</name>
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</author>
<author><name sortKey="Gennery, Andrew" sort="Gennery, Andrew" uniqKey="Gennery A" first="Andrew" last="Gennery">Andrew Gennery</name>
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<author><name sortKey="Fischer, Alain" sort="Fischer, Alain" uniqKey="Fischer A" first="Alain" last="Fischer">Alain Fischer</name>
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</author>
<author><name sortKey="Gaspar, H Bobby" sort="Gaspar, H Bobby" uniqKey="Gaspar H" first="H. Bobby" last="Gaspar">H. Bobby Gaspar</name>
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</placeName>
</affiliation>
<affiliation wicri:level="3"><inist:fA14 i1="18"><s1>Molecular Immunology Unit; UCL Institute of Child Health</s1>
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<author><name sortKey="Schanz, Urs" sort="Schanz, Urs" uniqKey="Schanz U" first="Urs" last="Schanz">Urs Schanz</name>
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<author><name sortKey="Seger, Reinhard" sort="Seger, Reinhard" uniqKey="Seger R" first="Reinhard" last="Seger">Reinhard Seger</name>
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<author><name sortKey="Rentsch, Katharina" sort="Rentsch, Katharina" uniqKey="Rentsch K" first="Katharina" last="Rentsch">Katharina Rentsch</name>
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<author><name sortKey="Veys, Paul" sort="Veys, Paul" uniqKey="Veys P" first="Paul" last="Veys">Paul Veys</name>
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</placeName>
</affiliation>
<affiliation wicri:level="3"><inist:fA14 i1="18"><s1>Molecular Immunology Unit; UCL Institute of Child Health</s1>
<s2>London</s2>
<s3>GBR</s3>
<sZ>23 aut.</sZ>
<sZ>27 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Haddad, Elie" sort="Haddad, Elie" uniqKey="Haddad E" first="Elie" last="Haddad">Elie Haddad</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Centre de Recherche du CHU Sainte-Justine, Département de Pédiatrie, Université de Montréal</s1>
<s2>Montréal, QC</s2>
<s3>CAN</s3>
<sZ>2 aut.</sZ>
<sZ>28 aut.</sZ>
</inist:fA14>
<country>Canada</country>
<wicri:noRegion>Montréal, QC</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Albert, Michael H" sort="Albert, Michael H" uniqKey="Albert M" first="Michael H." last="Albert">Michael H. Albert</name>
<affiliation wicri:level="3"><inist:fA14 i1="16"><s1>Dr von Hauner University Children's Hospital</s1>
<s2>Munich</s2>
<s3>DEU</s3>
<sZ>20 aut.</sZ>
<sZ>29 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<placeName><region type="land" nuts="1">Bavière</region>
<region type="district" nuts="2">District de Haute-Bavière</region>
<settlement type="city">Munich</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hassan, Moustapha" sort="Hassan, Moustapha" uniqKey="Hassan M" first="Moustapha" last="Hassan">Moustapha Hassan</name>
<affiliation wicri:level="1"><inist:fA14 i1="20"><s1>Division of Experimental Cancer Medicine, KFC, Novum, Laboratory Medicine, Karolinska University Hospital-Huddinge Stockholm</s1>
<s3>SWE</s3>
<sZ>30 aut.</sZ>
</inist:fA14>
<country>Suède</country>
<wicri:noRegion>Division of Experimental Cancer Medicine, KFC, Novum, Laboratory Medicine, Karolinska University Hospital-Huddinge Stockholm</wicri:noRegion>
</affiliation>
<affiliation wicri:level="3"><inist:fA14 i1="21"><s1>Karolinska Institute</s1>
<s2>Stockholm</s2>
<s3>SWE</s3>
<sZ>30 aut.</sZ>
</inist:fA14>
<country>Suède</country>
<placeName><settlement type="city">Stockholm</settlement>
<region nuts="2">Svealand</region>
</placeName>
</affiliation>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Reduced-intensity conditioning and HLA-matched haemopoietic stem-cell transplantation in patients with chronic granulomatous disease: a prospective multicentre study</title>
<author><name sortKey="Gungor, Tayfun" sort="Gungor, Tayfun" uniqKey="Gungor T" first="Tayfun" last="Güngör">Tayfun Güngör</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>University Children's Hospital, Division of Blood and Marrow Transplantation</s1>
<s2>Zurich</s2>
<s3>CHE</s3>
<sZ>1 aut.</sZ>
<sZ>25 aut.</sZ>
</inist:fA14>
<country>Suisse</country>
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</affiliation>
</author>
<author><name sortKey="Teira, Pierre" sort="Teira, Pierre" uniqKey="Teira P" first="Pierre" last="Teira">Pierre Teira</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Centre de Recherche du CHU Sainte-Justine, Département de Pédiatrie, Université de Montréal</s1>
<s2>Montréal, QC</s2>
<s3>CAN</s3>
<sZ>2 aut.</sZ>
<sZ>28 aut.</sZ>
</inist:fA14>
<country>Canada</country>
<wicri:noRegion>Montréal, QC</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Slatter, Mary" sort="Slatter, Mary" uniqKey="Slatter M" first="Mary" last="Slatter">Mary Slatter</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Institute of Cellular Medicine, Newcastle University</s1>
<s2>Newcastle upon Tyne</s2>
<s3>GBR</s3>
<sZ>3 aut.</sZ>
<sZ>21 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<wicri:noRegion>Newcastle upon Tyne</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Stussi, Georg" sort="Stussi, Georg" uniqKey="Stussi G" first="Georg" last="Stussi">Georg Stussi</name>
<affiliation wicri:level="3"><inist:fA14 i1="04"><s1>University Hospital, Division of Hematology and Blood and Marrow Transplantation</s1>
<s2>Zürich</s2>
<s3>CHE</s3>
<sZ>4 aut.</sZ>
<sZ>24 aut.</sZ>
</inist:fA14>
<country>Suisse</country>
<placeName><settlement type="city">Zurich</settlement>
<region nuts="3" type="region">Canton de Zurich</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Stepensky, Polina" sort="Stepensky, Polina" uniqKey="Stepensky P" first="Polina" last="Stepensky">Polina Stepensky</name>
<affiliation wicri:level="1"><inist:fA14 i1="05"><s1>Hadassah Hebrew University Medical Center, Department of Blood and Marrow Transplantation</s1>
<s2>Jerusalem</s2>
<s3>ISR</s3>
<sZ>5 aut.</sZ>
<sZ>19 aut.</sZ>
</inist:fA14>
<country>Israël</country>
<wicri:noRegion>Jerusalem</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Moshous, Despina" sort="Moshous, Despina" uniqKey="Moshous D" first="Despina" last="Moshous">Despina Moshous</name>
<affiliation wicri:level="4"><inist:fA14 i1="06"><s1>AP-HP, Hôpital Necker Enfants Malades, Paediatric Immunology, Sorbonne Paris Cité, Université Paris Descartes, Imagine Institute</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>6 aut.</sZ>
<sZ>22 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
<settlement type="city">Paris</settlement>
</placeName>
<orgName type="university">Université Paris-Descartes</orgName>
</affiliation>
</author>
<author><name sortKey="Vermont, Clementien" sort="Vermont, Clementien" uniqKey="Vermont C" first="Clementien" last="Vermont">Clementien Vermont</name>
<affiliation wicri:level="3"><inist:fA14 i1="07"><s1>Leiden University Medical Center, Department of Paediatrics</s1>
<s2>Leiden</s2>
<s3>NLD</s3>
<sZ>7 aut.</sZ>
<sZ>18 aut.</sZ>
</inist:fA14>
<country>Pays-Bas</country>
<placeName><settlement type="city">Leyde</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Ahmad, Imran" sort="Ahmad, Imran" uniqKey="Ahmad I" first="Imran" last="Ahmad">Imran Ahmad</name>
<affiliation wicri:level="1"><inist:fA14 i1="08"><s1>Blood and Marrow Transplantation Program, Hôpital Maisonneuve-Rosemont, Université de Montréal</s1>
<s2>Montréal, QC</s2>
<s3>CAN</s3>
<sZ>8 aut.</sZ>
<sZ>17 aut.</sZ>
</inist:fA14>
<country>Canada</country>
<wicri:noRegion>Montréal, QC</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Shaw, Peter J" sort="Shaw, Peter J" uniqKey="Shaw P" first="Peter J." last="Shaw">Peter J. Shaw</name>
<affiliation wicri:level="1"><inist:fA14 i1="09"><s1>Children's Hospital, Division of Blood and Marrow Transplantation</s1>
<s2>Westmead, Sydney, NSW</s2>
<s3>AUS</s3>
<sZ>9 aut.</sZ>
</inist:fA14>
<country>Australie</country>
<wicri:noRegion>Westmead, Sydney, NSW</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Da Cunha, Jose Marcos Telles" sort="Da Cunha, Jose Marcos Telles" uniqKey="Da Cunha J" first="José Marcos Telles" last="Da Cunha">José Marcos Telles Da Cunha</name>
<affiliation wicri:level="3"><inist:fA14 i1="10"><s1>Hospital Albert Einstein, Haematology and Hematopoietic stem cell transplantation Unit</s1>
<s2>Sao Paulo</s2>
<s3>BRA</s3>
<sZ>10 aut.</sZ>
</inist:fA14>
<country>Brésil</country>
<placeName><settlement type="city">São Paulo</settlement>
<region type="state">État de São Paulo</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Schlegel, Paul G" sort="Schlegel, Paul G" uniqKey="Schlegel P" first="Paul G." last="Schlegel">Paul G. Schlegel</name>
<affiliation wicri:level="3"><inist:fA14 i1="11"><s1>University Children's Hospital, Division of Blood and Marrow Transplantation</s1>
<s2>Würzburg</s2>
<s3>DEU</s3>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<placeName><region type="land" nuts="1">Bavière</region>
<region type="district" nuts="2">District de Basse-Franconie</region>
<settlement type="city">Wurtzbourg</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hough, Rachel" sort="Hough, Rachel" uniqKey="Hough R" first="Rachel" last="Hough">Rachel Hough</name>
<affiliation wicri:level="3"><inist:fA14 i1="12"><s1>University College London Hospitals NHS Foundation Trust</s1>
<s2>London</s2>
<s3>GBR</s3>
<sZ>12 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Fasth, Anders" sort="Fasth, Anders" uniqKey="Fasth A" first="Anders" last="Fasth">Anders Fasth</name>
<affiliation wicri:level="1"><inist:fA14 i1="13"><s1>Department of Pediatrics, University of Gothenburg</s1>
<s2>Gothenburg</s2>
<s3>SWE</s3>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>Suède</country>
<wicri:noRegion>Gothenburg</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kentouche, Karim" sort="Kentouche, Karim" uniqKey="Kentouche K" first="Karim" last="Kentouche">Karim Kentouche</name>
<affiliation wicri:level="1"><inist:fA14 i1="14"><s1>Department of Paediatrics, Jena University Hospital</s1>
<s2>Jena</s2>
<s3>DEU</s3>
<sZ>14 aut.</sZ>
<sZ>15 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>Jena</wicri:noRegion>
<wicri:noRegion>Jena University Hospital</wicri:noRegion>
<wicri:noRegion>Jena</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Gruhn, Bernd" sort="Gruhn, Bernd" uniqKey="Gruhn B" first="Bernd" last="Gruhn">Bernd Gruhn</name>
<affiliation wicri:level="1"><inist:fA14 i1="14"><s1>Department of Paediatrics, Jena University Hospital</s1>
<s2>Jena</s2>
<s3>DEU</s3>
<sZ>14 aut.</sZ>
<sZ>15 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>Jena</wicri:noRegion>
<wicri:noRegion>Jena University Hospital</wicri:noRegion>
<wicri:noRegion>Jena</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Fernandes, Juliana F" sort="Fernandes, Juliana F" uniqKey="Fernandes J" first="Juliana F." last="Fernandes">Juliana F. Fernandes</name>
<affiliation wicri:level="4"><inist:fA14 i1="15"><s1>Instituto da Criança, Universidade de São Paulo</s1>
<s2>São Paulo</s2>
<s3>BRA</s3>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>Brésil</country>
<placeName><settlement type="city">São Paulo</settlement>
<region type="state">État de São Paulo</region>
<settlement type="city">São Paulo</settlement>
</placeName>
<orgName type="university">Université de São Paulo</orgName>
</affiliation>
</author>
<author><name sortKey="Lachance, Silvy" sort="Lachance, Silvy" uniqKey="Lachance S" first="Silvy" last="Lachance">Silvy Lachance</name>
<affiliation wicri:level="1"><inist:fA14 i1="08"><s1>Blood and Marrow Transplantation Program, Hôpital Maisonneuve-Rosemont, Université de Montréal</s1>
<s2>Montréal, QC</s2>
<s3>CAN</s3>
<sZ>8 aut.</sZ>
<sZ>17 aut.</sZ>
</inist:fA14>
<country>Canada</country>
<wicri:noRegion>Montréal, QC</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Bredius, Robbert" sort="Bredius, Robbert" uniqKey="Bredius R" first="Robbert" last="Bredius">Robbert Bredius</name>
<affiliation wicri:level="3"><inist:fA14 i1="07"><s1>Leiden University Medical Center, Department of Paediatrics</s1>
<s2>Leiden</s2>
<s3>NLD</s3>
<sZ>7 aut.</sZ>
<sZ>18 aut.</sZ>
</inist:fA14>
<country>Pays-Bas</country>
<placeName><settlement type="city">Leyde</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Resnick, Igor B" sort="Resnick, Igor B" uniqKey="Resnick I" first="Igor B." last="Resnick">Igor B. Resnick</name>
<affiliation wicri:level="1"><inist:fA14 i1="05"><s1>Hadassah Hebrew University Medical Center, Department of Blood and Marrow Transplantation</s1>
<s2>Jerusalem</s2>
<s3>ISR</s3>
<sZ>5 aut.</sZ>
<sZ>19 aut.</sZ>
</inist:fA14>
<country>Israël</country>
<wicri:noRegion>Jerusalem</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Belohradsky, Bernd H" sort="Belohradsky, Bernd H" uniqKey="Belohradsky B" first="Bernd H." last="Belohradsky">Bernd H. Belohradsky</name>
<affiliation wicri:level="3"><inist:fA14 i1="16"><s1>Dr von Hauner University Children's Hospital</s1>
<s2>Munich</s2>
<s3>DEU</s3>
<sZ>20 aut.</sZ>
<sZ>29 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<placeName><region type="land" nuts="1">Bavière</region>
<region type="district" nuts="2">District de Haute-Bavière</region>
<settlement type="city">Munich</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gennery, Andrew" sort="Gennery, Andrew" uniqKey="Gennery A" first="Andrew" last="Gennery">Andrew Gennery</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Institute of Cellular Medicine, Newcastle University</s1>
<s2>Newcastle upon Tyne</s2>
<s3>GBR</s3>
<sZ>3 aut.</sZ>
<sZ>21 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<wicri:noRegion>Newcastle upon Tyne</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Fischer, Alain" sort="Fischer, Alain" uniqKey="Fischer A" first="Alain" last="Fischer">Alain Fischer</name>
<affiliation wicri:level="4"><inist:fA14 i1="06"><s1>AP-HP, Hôpital Necker Enfants Malades, Paediatric Immunology, Sorbonne Paris Cité, Université Paris Descartes, Imagine Institute</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>6 aut.</sZ>
<sZ>22 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
<settlement type="city">Paris</settlement>
</placeName>
<orgName type="university">Université Paris-Descartes</orgName>
</affiliation>
</author>
<author><name sortKey="Gaspar, H Bobby" sort="Gaspar, H Bobby" uniqKey="Gaspar H" first="H. Bobby" last="Gaspar">H. Bobby Gaspar</name>
<affiliation wicri:level="3"><inist:fA14 i1="17"><s1>Great Ormond Street Children's Hospital, Division of Blood and Marrow Transplantation</s1>
<s2>London</s2>
<s3>GBR</s3>
<sZ>23 aut.</sZ>
<sZ>27 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
<affiliation wicri:level="3"><inist:fA14 i1="18"><s1>Molecular Immunology Unit; UCL Institute of Child Health</s1>
<s2>London</s2>
<s3>GBR</s3>
<sZ>23 aut.</sZ>
<sZ>27 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Schanz, Urs" sort="Schanz, Urs" uniqKey="Schanz U" first="Urs" last="Schanz">Urs Schanz</name>
<affiliation wicri:level="3"><inist:fA14 i1="04"><s1>University Hospital, Division of Hematology and Blood and Marrow Transplantation</s1>
<s2>Zürich</s2>
<s3>CHE</s3>
<sZ>4 aut.</sZ>
<sZ>24 aut.</sZ>
</inist:fA14>
<country>Suisse</country>
<placeName><settlement type="city">Zurich</settlement>
<region nuts="3" type="region">Canton de Zurich</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Seger, Reinhard" sort="Seger, Reinhard" uniqKey="Seger R" first="Reinhard" last="Seger">Reinhard Seger</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>University Children's Hospital, Division of Blood and Marrow Transplantation</s1>
<s2>Zurich</s2>
<s3>CHE</s3>
<sZ>1 aut.</sZ>
<sZ>25 aut.</sZ>
</inist:fA14>
<country>Suisse</country>
<wicri:noRegion>Zurich</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Rentsch, Katharina" sort="Rentsch, Katharina" uniqKey="Rentsch K" first="Katharina" last="Rentsch">Katharina Rentsch</name>
<affiliation wicri:level="1"><inist:fA14 i1="19"><s1>University Hospital, Divison of Clinical Chemistry, KFC, Novum, Laboratory Medicine, Karolinska University Hospital-Huddinge Stockholm</s1>
<s3>SWE</s3>
<sZ>26 aut.</sZ>
</inist:fA14>
<country>Suède</country>
<wicri:noRegion>University Hospital, Divison of Clinical Chemistry, KFC, Novum, Laboratory Medicine, Karolinska University Hospital-Huddinge Stockholm</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Veys, Paul" sort="Veys, Paul" uniqKey="Veys P" first="Paul" last="Veys">Paul Veys</name>
<affiliation wicri:level="3"><inist:fA14 i1="17"><s1>Great Ormond Street Children's Hospital, Division of Blood and Marrow Transplantation</s1>
<s2>London</s2>
<s3>GBR</s3>
<sZ>23 aut.</sZ>
<sZ>27 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
<affiliation wicri:level="3"><inist:fA14 i1="18"><s1>Molecular Immunology Unit; UCL Institute of Child Health</s1>
<s2>London</s2>
<s3>GBR</s3>
<sZ>23 aut.</sZ>
<sZ>27 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Haddad, Elie" sort="Haddad, Elie" uniqKey="Haddad E" first="Elie" last="Haddad">Elie Haddad</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Centre de Recherche du CHU Sainte-Justine, Département de Pédiatrie, Université de Montréal</s1>
<s2>Montréal, QC</s2>
<s3>CAN</s3>
<sZ>2 aut.</sZ>
<sZ>28 aut.</sZ>
</inist:fA14>
<country>Canada</country>
<wicri:noRegion>Montréal, QC</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Albert, Michael H" sort="Albert, Michael H" uniqKey="Albert M" first="Michael H." last="Albert">Michael H. Albert</name>
<affiliation wicri:level="3"><inist:fA14 i1="16"><s1>Dr von Hauner University Children's Hospital</s1>
<s2>Munich</s2>
<s3>DEU</s3>
<sZ>20 aut.</sZ>
<sZ>29 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<placeName><region type="land" nuts="1">Bavière</region>
<region type="district" nuts="2">District de Haute-Bavière</region>
<settlement type="city">Munich</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hassan, Moustapha" sort="Hassan, Moustapha" uniqKey="Hassan M" first="Moustapha" last="Hassan">Moustapha Hassan</name>
<affiliation wicri:level="1"><inist:fA14 i1="20"><s1>Division of Experimental Cancer Medicine, KFC, Novum, Laboratory Medicine, Karolinska University Hospital-Huddinge Stockholm</s1>
<s3>SWE</s3>
<sZ>30 aut.</sZ>
</inist:fA14>
<country>Suède</country>
<wicri:noRegion>Division of Experimental Cancer Medicine, KFC, Novum, Laboratory Medicine, Karolinska University Hospital-Huddinge Stockholm</wicri:noRegion>
</affiliation>
<affiliation wicri:level="3"><inist:fA14 i1="21"><s1>Karolinska Institute</s1>
<s2>Stockholm</s2>
<s3>SWE</s3>
<sZ>30 aut.</sZ>
</inist:fA14>
<country>Suède</country>
<placeName><settlement type="city">Stockholm</settlement>
<region nuts="2">Svealand</region>
</placeName>
</affiliation>
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</analytic>
<series><title level="j" type="main">Lancet : (British edition)</title>
<title level="j" type="abbreviated">Lancet : (Br. ed.)</title>
<idno type="ISSN">0140-6736</idno>
<imprint><date when="2014">2014</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Lancet : (British edition)</title>
<title level="j" type="abbreviated">Lancet : (Br. ed.)</title>
<idno type="ISSN">0140-6736</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Chronic granulomatous disease</term>
<term>HLA-System</term>
<term>Hematopoietic cell</term>
<term>Homograft</term>
<term>Human</term>
<term>Major histocompatibility system</term>
<term>Medicine</term>
<term>Multicenter study</term>
<term>Non myeloablative treatment</term>
<term>Patient</term>
<term>Prospective</term>
<term>Stem cell</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Conditionnement atténué</term>
<term>Système HLA</term>
<term>Système histocompatibilité majeur</term>
<term>Homogreffe</term>
<term>Cellule hématopoïétique</term>
<term>Cellule souche</term>
<term>Granulomatose chronique</term>
<term>Homme</term>
<term>Malade</term>
<term>Prospective</term>
<term>Etude multicentrique</term>
<term>Médecine</term>
<term>Granulomatose chronique familiale</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Cellule souche</term>
<term>Homme</term>
<term>Prospective</term>
<term>Médecine</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Background In chronic granulomatous disease allogeneic haemopoietic stem-cell transplantation (HSCT) in adolescents and young adults and patients with high-risk disease is complicated by graft-failure, graft-versus-host disease (GVHD), and transplant-related mortality. We examined the effect of a reduced-intensity conditioning regimen designed to enhance myeloid engraftment and reduce organ toxicity in these patients.</div>
</front>
</TEI>
<affiliations><list><country><li>Allemagne</li>
<li>Australie</li>
<li>Brésil</li>
<li>Canada</li>
<li>France</li>
<li>Israël</li>
<li>Pays-Bas</li>
<li>Royaume-Uni</li>
<li>Suisse</li>
<li>Suède</li>
</country>
<region><li>Angleterre</li>
<li>Bavière</li>
<li>Canton de Zurich</li>
<li>District de Basse-Franconie</li>
<li>District de Haute-Bavière</li>
<li>Grand Londres</li>
<li>Hollande-Méridionale</li>
<li>Svealand</li>
<li>État de São Paulo</li>
<li>Île-de-France</li>
</region>
<settlement><li>Leyde</li>
<li>Londres</li>
<li>Munich</li>
<li>Paris</li>
<li>Stockholm</li>
<li>São Paulo</li>
<li>Wurtzbourg</li>
<li>Zurich</li>
</settlement>
<orgName><li>Université Paris-Descartes</li>
<li>Université de São Paulo</li>
</orgName>
</list>
<tree><country name="Suisse"><noRegion><name sortKey="Gungor, Tayfun" sort="Gungor, Tayfun" uniqKey="Gungor T" first="Tayfun" last="Güngör">Tayfun Güngör</name>
</noRegion>
<name sortKey="Schanz, Urs" sort="Schanz, Urs" uniqKey="Schanz U" first="Urs" last="Schanz">Urs Schanz</name>
<name sortKey="Seger, Reinhard" sort="Seger, Reinhard" uniqKey="Seger R" first="Reinhard" last="Seger">Reinhard Seger</name>
<name sortKey="Stussi, Georg" sort="Stussi, Georg" uniqKey="Stussi G" first="Georg" last="Stussi">Georg Stussi</name>
</country>
<country name="Canada"><noRegion><name sortKey="Teira, Pierre" sort="Teira, Pierre" uniqKey="Teira P" first="Pierre" last="Teira">Pierre Teira</name>
</noRegion>
<name sortKey="Ahmad, Imran" sort="Ahmad, Imran" uniqKey="Ahmad I" first="Imran" last="Ahmad">Imran Ahmad</name>
<name sortKey="Haddad, Elie" sort="Haddad, Elie" uniqKey="Haddad E" first="Elie" last="Haddad">Elie Haddad</name>
<name sortKey="Lachance, Silvy" sort="Lachance, Silvy" uniqKey="Lachance S" first="Silvy" last="Lachance">Silvy Lachance</name>
</country>
<country name="Royaume-Uni"><noRegion><name sortKey="Slatter, Mary" sort="Slatter, Mary" uniqKey="Slatter M" first="Mary" last="Slatter">Mary Slatter</name>
</noRegion>
<name sortKey="Gaspar, H Bobby" sort="Gaspar, H Bobby" uniqKey="Gaspar H" first="H. Bobby" last="Gaspar">H. Bobby Gaspar</name>
<name sortKey="Gaspar, H Bobby" sort="Gaspar, H Bobby" uniqKey="Gaspar H" first="H. Bobby" last="Gaspar">H. Bobby Gaspar</name>
<name sortKey="Gennery, Andrew" sort="Gennery, Andrew" uniqKey="Gennery A" first="Andrew" last="Gennery">Andrew Gennery</name>
<name sortKey="Hough, Rachel" sort="Hough, Rachel" uniqKey="Hough R" first="Rachel" last="Hough">Rachel Hough</name>
<name sortKey="Veys, Paul" sort="Veys, Paul" uniqKey="Veys P" first="Paul" last="Veys">Paul Veys</name>
<name sortKey="Veys, Paul" sort="Veys, Paul" uniqKey="Veys P" first="Paul" last="Veys">Paul Veys</name>
</country>
<country name="Israël"><noRegion><name sortKey="Stepensky, Polina" sort="Stepensky, Polina" uniqKey="Stepensky P" first="Polina" last="Stepensky">Polina Stepensky</name>
</noRegion>
<name sortKey="Resnick, Igor B" sort="Resnick, Igor B" uniqKey="Resnick I" first="Igor B." last="Resnick">Igor B. Resnick</name>
</country>
<country name="France"><region name="Île-de-France"><name sortKey="Moshous, Despina" sort="Moshous, Despina" uniqKey="Moshous D" first="Despina" last="Moshous">Despina Moshous</name>
</region>
<name sortKey="Fischer, Alain" sort="Fischer, Alain" uniqKey="Fischer A" first="Alain" last="Fischer">Alain Fischer</name>
</country>
<country name="Pays-Bas"><region name="Hollande-Méridionale"><name sortKey="Vermont, Clementien" sort="Vermont, Clementien" uniqKey="Vermont C" first="Clementien" last="Vermont">Clementien Vermont</name>
</region>
<name sortKey="Bredius, Robbert" sort="Bredius, Robbert" uniqKey="Bredius R" first="Robbert" last="Bredius">Robbert Bredius</name>
</country>
<country name="Australie"><noRegion><name sortKey="Shaw, Peter J" sort="Shaw, Peter J" uniqKey="Shaw P" first="Peter J." last="Shaw">Peter J. Shaw</name>
</noRegion>
</country>
<country name="Brésil"><region name="État de São Paulo"><name sortKey="Da Cunha, Jose Marcos Telles" sort="Da Cunha, Jose Marcos Telles" uniqKey="Da Cunha J" first="José Marcos Telles" last="Da Cunha">José Marcos Telles Da Cunha</name>
</region>
<name sortKey="Fernandes, Juliana F" sort="Fernandes, Juliana F" uniqKey="Fernandes J" first="Juliana F." last="Fernandes">Juliana F. Fernandes</name>
</country>
<country name="Allemagne"><region name="Bavière"><name sortKey="Schlegel, Paul G" sort="Schlegel, Paul G" uniqKey="Schlegel P" first="Paul G." last="Schlegel">Paul G. Schlegel</name>
</region>
<name sortKey="Albert, Michael H" sort="Albert, Michael H" uniqKey="Albert M" first="Michael H." last="Albert">Michael H. Albert</name>
<name sortKey="Belohradsky, Bernd H" sort="Belohradsky, Bernd H" uniqKey="Belohradsky B" first="Bernd H." last="Belohradsky">Bernd H. Belohradsky</name>
<name sortKey="Gruhn, Bernd" sort="Gruhn, Bernd" uniqKey="Gruhn B" first="Bernd" last="Gruhn">Bernd Gruhn</name>
<name sortKey="Kentouche, Karim" sort="Kentouche, Karim" uniqKey="Kentouche K" first="Karim" last="Kentouche">Karim Kentouche</name>
</country>
<country name="Suède"><noRegion><name sortKey="Fasth, Anders" sort="Fasth, Anders" uniqKey="Fasth A" first="Anders" last="Fasth">Anders Fasth</name>
</noRegion>
<name sortKey="Hassan, Moustapha" sort="Hassan, Moustapha" uniqKey="Hassan M" first="Moustapha" last="Hassan">Moustapha Hassan</name>
<name sortKey="Hassan, Moustapha" sort="Hassan, Moustapha" uniqKey="Hassan M" first="Moustapha" last="Hassan">Moustapha Hassan</name>
<name sortKey="Rentsch, Katharina" sort="Rentsch, Katharina" uniqKey="Rentsch K" first="Katharina" last="Rentsch">Katharina Rentsch</name>
</country>
</tree>
</affiliations>
</record>

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   |texte=   Reduced-intensity conditioning and HLA-matched haemopoietic stem-cell transplantation in patients with chronic granulomatous disease: a prospective multicentre study
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This area was generated with Dilib version V0.6.33.
Data generation: Tue Dec 5 10:43:12 2017. Site generation: Tue Mar 5 14:07:20 2024

	Serveur d'exploration sur les relations entre la France et l'Australie
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Serveur d'exploration sur les relations entre la France et l'Australie

Reduced-intensity conditioning and HLA-matched haemopoietic stem-cell transplantation in patients with chronic granulomatous disease: a prospective multicentre study

Reduced-intensity conditioning and HLA-matched haemopoietic stem-cell transplantation in patients with chronic granulomatous disease: a prospective multicentre study

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